![]() When side effects do occur, they typically consist of minor gastrointestinal symptoms. Omega-3 fatty acid supplements usually do not have negative side effects.Further, another 2017 systematic review with network meta-analyses of 190 randomized trials found that there is a lack of evidence for complementary health approaches, including fatty acids, for the treatment of ADHD in children and adolescents. Of the studies included in the review, there were variations in sample size, study duration, type, and dosage of supplementation, making it difficult to compare the findings and draw firm conclusions about the efficacy. However, a 2017 systematic review of 25 randomized controlled trials found about half of the studies reporting some beneficial effect of omega-3 fatty acids on ADHD symptoms, and half reporting negative results. A 2018 systematic review and meta-analysis of 8 studies involving a total of 628 participants found some evidence that omega-3 fatty acid supplementation monotherapy improves clinical symptoms and cognitive performances in children and adolescents with ADHD, and that these youth have a deficiency in omega-3 fatty acid levels. ![]() The best dosage ratio needs to be further studied, butseveral reported studies suggest a combination of a 9:3:1 ratio EPA, DHA, GLA is associated with improvement in ADHD symptoms. ![]()
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